Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590655 | 0.81 | L3MBTL1 (0.33) | TP53ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL11671829 | 0.80 | TDP1 (0.40) | TP53ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL9639909 | 0.79 | ALDH1A1 (0.36) | TP53ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL8587749 | 0.77 | TSHR (0.46) | TP53ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL11649577 | 0.76 | TSHR (0.54) | ALDH1A1SMN1; SMN2KMT2ATSHRCTSL | |
| SCHEMBL11652421 | 0.75 | MGLL (0.43) | ALDH1A1LMNANPSR1KMT2AGAA | |
| SCHEMBL11124613 | 0.74 | MAPT (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL10585519 | 0.71 | KMT2A (0.41) | ALDH1A1SMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL2323984 | 0.70 | TSHR (0.37) | TP53ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL10409312 | 0.70 | HSD17B10 (0.39) | TP53ALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960874-A | DYEING CELLULOSE ESTERS AND POLYESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| US-4764600-A | Isothiazolylazo dyes having aminophenyl and aminonaphthyl components | BASF AKTIENGESELLSCHAFT (DE) | 1988-08-16 | — | — | US | disclosed |
| US-4496480-A | Isothiazolazo dyes having coupling components which are free from unsaturated aliphatic radicals | BASF AKTIENGESELLSCHAFT (DE) | 1985-01-29 | — | — | US | disclosed |