Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11696463 | 0.89 | TP53 (0.42) | TSHRTP53POLBPDCD1CD274 | |
| SCHEMBL8519633 | 0.86 | TSHR (0.52) | TSHRTP53POLBPDCD1CD274 | |
| SCHEMBL9639909 | 0.85 | ALDH1A1 (0.36) | TSHRTP53LMNAALDH1A1HTT | |
| SCHEMBL11671829 | 0.81 | TDP1 (0.40) | TP53NPC1LMNAALDH1A1RAB9A | |
| SCHEMBL11649577 | 0.80 | TSHR (0.54) | TSHRPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11687320 | 0.78 | TSHR (0.44) | TSHRTP53POLBPDCD1CD274 | |
| SCHEMBL11124613 | 0.78 | MAPT (0.48) | NPC1ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL10409308 | 0.77 | TP53 (0.34) | TSHRTP53NPC1LMNAALDH1A1 | |
| SCHEMBL2323984 | 0.76 | TSHR (0.37) | TSHRTP53POLBNPC1LMNA | |
| SCHEMBL11652421 | 0.76 | MGLL (0.43) | TSHRLMNAALDH1A1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115044226-A | 3-amino-5-nitrobenzoisothiazole-based dye and preparation method thereof | 金塔县晋泰森新材料科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-108069875-B | Synthesis process of N-cyanoethyl-N-benzoyloxyethylaniline | 浙江龙盛化工研究有限公司 | 2021-10-08 | — | — | CN | claimed |
| JP-10251534-A | — | — | None | — | — | JP | disclosed |
| CN-115353751-B | Method for preparing monoazo disperse dye | 浙江闰土染料有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-115353751-A | Preparation method of monoazo disperse dye | 浙江闰土染料有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-115044226-A | 3-amino-5-nitrobenzoisothiazole-based dye and preparation method thereof | 金塔县晋泰森新材料科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-108069875-B | Synthesis process of N-cyanoethyl-N-benzoyloxyethylaniline | 浙江龙盛化工研究有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-108069875-B | Synthesis process of N-cyanoethyl-N-benzoyloxyethylaniline | 浙江龙盛化工研究有限公司 | 2021-10-08 | — | — | CN | disclosed |
| JP-H10251534-A | MIXTURE OF ORANGE COLOR-BASED DISPERSE DYE | DAISUTAA JAPAN KK | 1998-09-22 | — | — | JP | disclosed |
| EP-0228092-B1 | MIXED MONOAZO DYE AND METHOD OF DYEING POLYESTER FIBERS USING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4734101-A | DISPERSIBILITY, COLORFASTNESS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0228092-A2 | Mixed monoazo dye and method of dyeing polyester fibers using the same | MITSUBISHI KASEI CORPORATION (JP) | 1987-07-08 | — | — | EP | disclosed |