Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | HPGD | P15428 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409840 | 0.89 | KDM4E (0.66) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL10409879 | 0.87 | KDM4E (0.75) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL31218469 | 0.84 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL1088835 | 0.84 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL24943438 | 0.79 | KDM4E (0.74) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL10410862 | 0.79 | KDM4E (0.72) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL10409833 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL462229 | 0.76 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL7572742 | 0.75 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL462047 | 0.75 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957988-A | Process and polymers for the production of images | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |