Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | USP4 | Q13107 | 1/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726409 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPK1L3MBTL1CYP19A1TSHR | |
| SCHEMBL10410316 | 0.84 | TDP1 (0.46) | ALDH1A1MAPK1TSHRADRB2ADRB1 | |
| SCHEMBL10411816 | 0.82 | ALOX15 (0.42) | ALDH1A1MAPK1TSHRCHRM2CHRM4 | |
| SCHEMBL10410622 | 0.80 | CNR2 (0.51) | — | |
| SCHEMBL10411353 | 0.77 | MET (0.38) | ALDH1A1AKR1B10AKR1B1ESR1 | |
| SCHEMBL10411355 | 0.77 | MET (0.38) | ALDH1A1AKR1B10AKR1B1ESR1 | |
| SCHEMBL22283432 | 0.76 | TSHR (0.53) | ALDH1A1MAPK1L3MBTL1CYP19A1TSHR | |
| SCHEMBL10410261 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPK1TSHRADRB2ADRB1 | |
| SCHEMBL3508392 | 0.75 | CYP19A1 (0.46) | ALDH1A1MAPK1L3MBTL1CYP19A1TSHR | |
| SCHEMBL29655304 | 0.75 | CYP19A1 (0.46) | ALDH1A1MAPK1L3MBTL1CYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904815-A | PHENOLS WITH ESTER, ACID OR AMIDE FUNCTIONAL GROUPS, STABILIZERS FOR AQUEOUS OR ORGANIC SYSTEMS | CIBA-GEIGY AG (CH) | 1990-02-27 | — | — | US | disclosed |
| EP-0106799-B1 | PHENOLS AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1986-03-19 | — | — | EP | disclosed |