Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410316 | 0.89 | TDP1 (0.46) | ALDH1A1ESR1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL10411816 | 0.83 | ALOX15 (0.42) | ALDH1A1ESR1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL14552043 | 0.79 | NPC1 (0.38) | ALDH1A1NPC1MAPTRAB9AMAPK1 | |
| SCHEMBL10411355 | 0.78 | MET (0.38) | ALDH1A1ESR1LMNATDP1ESR2 | |
| SCHEMBL10411353 | 0.78 | MET (0.38) | ALDH1A1ESR1LMNATDP1ESR2 | |
| SCHEMBL21155024 | 0.77 | ESR1 (0.55) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL9627889 | 0.77 | ESR1 (0.60) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL9627881 | 0.77 | ESR1 (0.60) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL10410622 | 0.76 | CNR2 (0.51) | — | |
| SCHEMBL10410101 | 0.76 | ALDH1A1 (0.43) | ALDH1A1ESR1TSHRMAPK1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904815-A | PHENOLS WITH ESTER, ACID OR AMIDE FUNCTIONAL GROUPS, STABILIZERS FOR AQUEOUS OR ORGANIC SYSTEMS | CIBA-GEIGY AG (CH) | 1990-02-27 | — | — | US | disclosed |
| EP-0106799-B1 | PHENOLS AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1986-03-19 | — | — | EP | disclosed |
| EP-0106799-A1 | Phenols and their preparation | CIBA-GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |