Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | LTK | P29376 | 1/20 | 0.54 |
| ▸ | GRK5 | P34947 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2284267 | 0.86 | EGFR (0.72) | EGFRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL10411688 | 0.84 | SYK (0.58) | EGFRMEN1KMT2AMAPTSYK | |
| SCHEMBL22191547 | 0.81 | SYK (0.60) | EGFRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL29622027 | 0.80 | ROCK1 (0.63) | EGFRMEN1KMT2AMAPTNPC1 | |
| SCHEMBL1085867 | 0.80 | MEN1 (0.71) | EGFRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL28736394 | 0.78 | EGFR (0.58) | EGFRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4544861 | 0.78 | KCNH3 (0.70) | EGFRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4544834 | 0.78 | KCNH3 (0.70) | EGFRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL13302353 | 0.78 | MEN1 (0.69) | EGFRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL10412682 | 0.77 | NFKB1 (0.57) | EGFRMAPK1KCNH3SYKPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939243-A | Water-soluble copper complex disazo compounds containg a chloro triazinylamino group and a group of the vinylsulfone series as fiber-reactive groups and their dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |