Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RNASEH1 | O60930 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411392 | 0.79 | GAA (0.42) | GAAPKMTSHRRNASEH1 | |
| SCHEMBL6759191 | 0.77 | GAA (0.54) | GRIN2BGRIN1GAAPKMTSHR | |
| SCHEMBL10411393 | 0.76 | GAA (0.42) | GAAPKMTSHR | |
| SCHEMBL11562006 | 0.76 | HTR6 (0.44) | GRIN2BGRIN1GAAPKMTSHR | |
| SCHEMBL9540471 | 0.74 | GRIN2B (0.77) | GRIN2BGRIN1GAAPKMTSHR | |
| SCHEMBL11681489 | 0.73 | CA2 (0.47) | GAATSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL6542830 | 0.72 | GAA (0.60) | GRIN2BGRIN1GAAPKMTSHR | |
| SCHEMBL6951804 | 0.69 | HTR6 (0.52) | GRIN2BGRIN1GAAPKMTSHR | |
| SCHEMBL3790024 | 0.68 | GAA (0.58) | GRIN2BGRIN1GAAPKMTSHR | |
| SCHEMBL8816584 | 0.67 | GAA (0.57) | GRIN2BGRIN1GAAPKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | claimed |
| US-4925853-A | Antiinflammatory, antiallergens, antiulcer agents | BEECHAM GROUP PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | disclosed |