Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542830 | 0.82 | GAA (0.60) | GAAHTR6NPC1ALDH1A1RAB9A | |
| SCHEMBL9847093 | 0.80 | CBFB (0.46) | GAANPC1RAB9ACBFB | |
| SCHEMBL4069917 | 0.78 | CBFB (0.45) | GAANPC1ALDH1A1RAB9ACBFB | |
| SCHEMBL5738714 | 0.78 | CBFB (0.45) | GAANPC1ALDH1A1RAB9ACBFB | |
| SCHEMBL23227712 | 0.78 | CBFB (0.45) | NPC1RAB9ACBFBKDM4EMAPT | |
| SCHEMBL10411536 | 0.77 | GRIN2B (0.49) | GAAHTR6NPC1ALDH1A1RAB9A | |
| SCHEMBL6755343 | 0.77 | CBFB (0.44) | GAANPC1ALDH1A1RAB9ACBFB | |
| SCHEMBL6757251 | 0.77 | CBFB (0.44) | NPC1RAB9ACBFBKDM4E | |
| SCHEMBL6756153 | 0.75 | KDM4E (0.44) | GAANPC1ALDH1A1RAB9ACBFB | |
| SCHEMBL6756137 | 0.74 | CBFB (0.42) | ALDH1A1CBFBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |