Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706721 | 0.77 | POLB (0.36) | POLBALDH1A1OPRM1LMNAATM | |
| SCHEMBL12057961 | 0.77 | POLB (0.36) | POLBALDH1A1OPRM1LMNAATM | |
| SCHEMBL15337099 | 0.76 | F10 (0.37) | POLBALDH1A1OPRM1LMNAATM | |
| SCHEMBL14979290 | 0.74 | POLB (0.34) | POLBALDH1A1OPRM1LMNAATM | |
| SCHEMBL7513123 | 0.74 | POLB (0.34) | POLBALDH1A1OPRM1LMNAATM | |
| SCHEMBL13537384 | 0.74 | POLB (0.34) | POLBALDH1A1OPRM1LMNAATM | |
| SCHEMBL12037372 | 0.73 | LMNA (0.35) | POLBALDH1A1OPRM1LMNAATM | |
| SCHEMBL8353589 | 0.73 | OPRM1 (0.36) | POLBALDH1A1OPRM1LMNAATM | |
| SCHEMBL7807558 | 0.71 | ALOX15 (0.38) | POLBALDH1A1OPRM1LMNAATM | |
| SCHEMBL7807553 | 0.71 | ALOX15 (0.38) | POLBALDH1A1OPRM1LMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274279-A1 | NITRIC OXIDE DONATING PROSTAMIDES | Nicox S.A. (FR) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009136281-A1 | NITRIC OXIDE DONATING PROSTAMIDES | NICOX S.A. (FR) | 2009-11-12 | — | — | WO | disclosed |