Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807558 | 1.00 | ALOX15 (0.38) | ALOX15GAAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL8485985 | 1.00 | ALOX15 (0.38) | ALOX15GAAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL12057961 | 0.89 | POLB (0.36) | ALOX15GAAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL30706721 | 0.89 | POLB (0.36) | ALOX15GAAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL8353589 | 0.84 | OPRM1 (0.36) | ALOX15GAAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL12037372 | 0.84 | LMNA (0.35) | ALOX15GAAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL11179315 | 0.76 | ALDH1A1 (0.37) | ALOX15GAAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL15325943 | 0.76 | ALDH1A1 (0.37) | ALOX15GAAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL5116398 | 0.75 | ALOX15 (0.42) | ALOX15GAAPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL18346711 | 0.75 | ALOX15 (0.42) | ALOX15GAAPOLBSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675123-B1 | Cyclopropane derivatives and method of preparing the same | AJINOMOTO KK (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-5925756-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5808134-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5777116-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5556994-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0675123-A1 | Cyclopropane derivatives and method of preparing the same | Ajinomoto Co., Inc. (JP) | 1995-10-04 | — | — | EP | disclosed |