Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414102 | 0.74 | SLC6A4 (0.36) | KMT2APOLBHSP90AA1MEN1CYP19A1 | |
| SCHEMBL9362870 | 0.73 | APP (0.43) | CYP3A4LMNA | |
| SCHEMBL9362865 | 0.73 | APP (0.43) | CYP3A4LMNA | |
| SCHEMBL9467685 | 0.71 | POLB (0.38) | KMT2AMAPTPOLBHSP90AA1CYP3A4 | |
| SCHEMBL9467692 | 0.71 | POLB (0.38) | KMT2AMAPTPOLBHSP90AA1CYP3A4 | |
| SCHEMBL10568532 | 0.70 | HSP90AA1 (0.47) | KMT2AHSP90AA1CYP3A4GRM7LMNA | |
| SCHEMBL10360787 | 0.66 | HSP90AA1 (0.42) | KMT2APOLBHSP90AA1CYP3A4MEN1 | |
| SCHEMBL9366526 | 0.66 | ALDH1A1 (0.42) | KMT2AMAPTCYP3A4MEN1CYP19A1 | |
| SCHEMBL10565684 | 0.66 | CYP19A1 (0.40) | KMT2APOLBHSP90AA1CYP3A4MEN1 | |
| SCHEMBL10565622 | 0.66 | PDE2A (0.44) | KMT2APOLBHSP90AA1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962118-A | ACTIVE AGAINST ASPERGILLUS, CHAETOMIUM, PENICILLUM; WHEAT, BARLEY | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | claimed |