Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 7/20 | 0.61 |
| ▸ | SHBG | P04278 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.61 |
| ▸ | BLM | P54132 | 4/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602768 | 0.91 | AR (0.66) | ARLMNASHBGSMN1; SMN2HSD17B10 | |
| SCHEMBL11581843 | 0.89 | AR (0.69) | ARLMNASHBGSMN1; SMN2HSD17B10 | |
| SCHEMBL11045530 | 0.88 | LMNA (0.69) | ARLMNASHBGSMN1; SMN2HSD17B10 | |
| SCHEMBL7209282 | 0.88 | SHBG (0.65) | ARLMNASHBGSMN1; SMN2HSD17B10 | |
| SCHEMBL24358693 | 0.85 | SHBG (0.62) | ARLMNASHBGSMN1; SMN2HSD17B10 | |
| SCHEMBL3129400 | 0.83 | HSD17B10 (0.82) | ARLMNASHBGSMN1; SMN2HSD17B10 | |
| SCHEMBL24358664 | 0.83 | HSD17B10 (0.82) | ARLMNASHBGSMN1; SMN2HSD17B10 | |
| SCHEMBL11510015 | 0.83 | LMNA (0.77) | ARLMNASHBGSMN1; SMN2HSD17B10 | |
| SCHEMBL22872790 | 0.83 | AR (0.77) | ARLMNASHBGSMN1; SMN2HSD17B10 | |
| SCHEMBL24966580 | 0.82 | AR (0.80) | ARLMNASHBGSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956482-A | Process for the preparation of pregnane derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0181442-B1 | PROCESS FOR THE PREPARATION OF PREGNANE DERIVATIVE | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-07-12 | — | — | EP | disclosed |
| US-4708823-A | 17 α-chloroethynyl pregnane derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | disclosed |
| EP-0181442-A1 | Process for the preparation of pregnane derivative | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-05-21 | — | — | EP | disclosed |