Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412514 | 0.90 | SLC6A2 (0.47) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL10413278 | 0.88 | SIGMAR1 (0.42) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL10412550 | 0.85 | DRD2 (0.44) | SIGMAR1DRD2DRD4DRD3HTR2A | |
| SCHEMBL10413239 | 0.85 | SIGMAR1 (0.47) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL10413760 | 0.85 | SLC18A3 (0.48) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL10414161 | 0.81 | DRD2 (0.47) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL9828281 | 0.81 | HTR1A (0.53) | HTR6KCNH2 | |
| SCHEMBL6991477 | 0.77 | DRD2 (0.71) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL10414220 | 0.76 | DRD2 (0.43) | SIGMAR1DRD2DRD4DRD3SLC6A2 | |
| Hydrochloric Acid SCHEMBL11222340 | 0.76 | DRD2 (0.70) | SIGMAR1MEN1TP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916143-A | Hydroxyindole esters | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |