Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258227 | 0.86 | ACHE (0.48) | ACHELMNACYP3A4TSHRTEAD4 | |
| SCHEMBL11311298 | 0.84 | ACHE (0.46) | ACHELMNACYP3A4TSHRTEAD4 | |
| SCHEMBL28004434 | 0.80 | ACHE (0.48) | ACHELMNACYP3A4TSHRTEAD4 | |
| SCHEMBL3874496 | 0.78 | SMN1; SMN2 (0.44) | ACHELMNATSHRMAPTMEN1 | |
| SCHEMBL10413329 | 0.77 | ACHE (0.44) | ACHELMNACYP3A4TSHRTEAD4 | |
| SCHEMBL8391550 | 0.77 | LTA4H (0.38) | LMNATSHRALDH1A1CA1CA2 | |
| SCHEMBL2383687 | 0.77 | ACHE (0.48) | ACHELMNACYP3A4TSHRTEAD4 | |
| SCHEMBL27275041 | 0.77 | ACHE (0.48) | ACHELMNACYP3A4TSHRTEAD4 | |
| P-Xylene SCHEMBL28755299 | 0.76 | LMNA (0.43) | ACHELMNATSHRMAPTMEN1 | |
| SCHEMBL11463261 | 0.75 | ACHE (0.46) | ACHELMNACYP3A4TSHRTEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958034-A | DISCOLORATION INHIBITION; REACTION OF OLEFIN AND MALEIC ANHYDRIDE IN ARYLFLUOROPHOSPHITE PRESENCE | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |