Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413755 | 0.93 | DRD2 (0.45) | DRD4DRD2DRD3HTR7PARP1 | |
| SCHEMBL10413621 | 0.90 | DRD2 (0.45) | DRD4DRD2DRD3MAOAMAOB | |
| SCHEMBL10412473 | 0.86 | KCNH2 (0.46) | DRD4DRD2DRD3HTR7HTR6 | |
| SCHEMBL10648787 | 0.85 | DRD2 (0.47) | DRD4DRD2DRD3MAOAMAOB | |
| SCHEMBL10412923 | 0.84 | SLC18A3 (0.47) | DRD4DRD2DRD3MAOAMAOB | |
| SCHEMBL10413270 | 0.83 | DRD2 (0.45) | DRD4DRD2DRD3HTR7KCNH2 | |
| SCHEMBL10413250 | 0.83 | DRD2 (0.45) | DRD4DRD2DRD3HTR7KCNH2 | |
| SCHEMBL10414157 | 0.82 | HTR6 (0.42) | DRD4DRD2DRD3HTR7HTR6 | |
| SCHEMBL10414220 | 0.82 | DRD2 (0.43) | DRD4DRD2DRD3MMP3HTR7 | |
| SCHEMBL10412510 | 0.81 | DRD2 (0.45) | DRD4DRD2DRD3HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916143-A | Hydroxyindole esters | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |