Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | GMNN | O75496 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153718 | 0.88 | LMNA (0.67) | LMNASMN1; SMN2ALOX15MMP12CYP1A2 | |
| SCHEMBL1584634 | 0.83 | — | — | |
| SCHEMBL31571128 | 0.83 | LMNA (0.56) | LMNASMN1; SMN2ALOX15MMP12CYP1A2 | |
| SCHEMBL13988077 | 0.81 | LMNA (0.50) | LMNASMN1; SMN2ALOX15MMP12CYP1A2 | |
| SCHEMBL27657335 | 0.80 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2ALOX15MMP12CYP1A2 | |
| SCHEMBL14930231 | 0.80 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2ALOX15MMP12CYP1A2 | |
| SCHEMBL15354284 | 0.80 | MEN1 (0.46) | LMNASMN1; SMN2ALOX15CYP1A2MEN1 | |
| SCHEMBL4923275 | 0.80 | LMNA (0.58) | LMNASMN1; SMN2ALOX15MMP12CYP1A2 | |
| SCHEMBL4923280 | 0.80 | LMNA (0.58) | LMNASMN1; SMN2ALOX15MMP12CYP1A2 | |
| SCHEMBL12136517 | 0.80 | MEN1 (0.46) | LMNASMN1; SMN2ALOX15CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037043-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2017-02-09 | — | — | US | disclosed |
| US-9334235-B2 | Plasmalogen compounds, pharmaceutical compositions containing the same and methods for treating diseases of the aging | PHENOMENOME DISCOVERIES INC. (CA) | 2016-05-10 | — | — | US | disclosed |
| US-8952047-B1 | Betaine compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2015-02-10 | — | — | US | disclosed |
| US-8569369-B2 | Amino acid compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569368-B2 | Amino acid compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130116312-A2 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHENOMENOME DISCOVERIES INC. (CA) | 2013-05-09 | — | — | US | disclosed |
| US-4980487-A | ANTIULCER AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1990-12-25 | — | — | US | disclosed |
| US-4891384-A | Valepotriate hydrin containing medicines used to treat uclers and motility disturbances | KALI-CHEMIC PHARMA GMBH (DE) | 1990-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037043-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | LMNA 117/4885SMN1; SMN2 204/4885ALOX15 123/4885 |
| US-20130116312-A2 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHOSPHO1, SGMS2, MBOAT1 | LMNA 1183/4885SMN1; SMN2 342/4885ALOX15 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.