SCHEMBL10415367

SCHEMBL10415367

CC(CCc1ccccc1)(c1ccc(C(=O)Cl)cc1)c1ccc(C(=O)Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.49
NPC1 O15118 3/20 0.49
HDAC1 Q13547 3/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
LMNA P02545 1/20 0.44
ESRRG P62508 1/20 0.42
ALDH1A1 P00352 3/20 0.41
ESR1 P03372 1/20 0.41
CYP3A4 P08684 1/20 0.41
ESR2 Q92731 1/20 0.41
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9514882 0.87 RAB9A (0.51) RAB9ANPC1HDAC1HDAC8HDAC3
SCHEMBL10599554 0.79 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2
SCHEMBL311387 0.78 ESR1 (0.56) LMNAESRRGALDH1A1ESR1CYP3A4
SCHEMBL7702725 0.77 HDAC1 (0.60) RAB9ANPC1HDAC1HDAC8HDAC3
SCHEMBL10414869 0.76 NPC1 (0.57) RAB9ANPC1LMNAALDH1A1MEN1
SCHEMBL13523929 0.75 MAOB (0.55) RAB9ANPC1ESRRGSMN1; SMN2
SCHEMBL16282704 0.74 MEN1 (0.41) RAB9ANPC1HDAC1HDAC8HDAC3
SCHEMBL11125011 0.73 S1PR1 (0.43) ESRRGSLC13A5
SCHEMBL24896001 0.73 SLC13A5 (0.49) RAB9ANPC1LMNAESRRGSLC13A5
SCHEMBL25620281 0.72 LTA4H (0.52) RAB9ANPC1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4910291-A From aromatic diacid MITSUBISHI RAYON COMPANY LTD. (JP) 1990-03-20 US disclosed
EP-0302516-A2 Optical article made of amorphous thermoplastic polyester resin MITSUBISHI RAYON CO., LTD. (JP) 1989-02-08 EP disclosed