SCHEMBL10599554

SCHEMBL10599554

CC(CCc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TAAR1 Q96RJ0 5/20 0.41
ATM Q13315 1/20 0.41
SLC6A2 P23975 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
OPRM1 P35372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24896001 0.88 SLC13A5 (0.49) CYP2C19
SCHEMBL13523929 0.86 MAOB (0.55) TAAR1SLC6A2CYP2A6HTR2ASMN1; SMN2
SCHEMBL311387 0.86 ESR1 (0.56) ALDH1A1HPGDHSD17B10SLC6A2CYP1A2
SCHEMBL25620281 0.83 LTA4H (0.52) ALDH1A1TAAR1ATMTDP1SMN1; SMN2
SCHEMBL3962014 0.82 TAAR1 (0.52) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL9514882 0.82 RAB9A (0.51) ALDH1A1
SCHEMBL10415367 0.79 RAB9A (0.49) ALDH1A1SMN1; SMN2
SCHEMBL27479368 0.78 DRD2 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL26326648 0.78 CYP2C19 (0.47) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL315316 0.78 ALDH1A1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2589643-B1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME SK CHEMICALS CO LTD (KR) 2017-09-20 EP disclosed
US-9142784-B2 Highly efficient carbazole-based compound, and organic electroluminescence device comprising same SK CHEMICALS CO., LTD. (KR) 2015-09-22 US disclosed
CN-102959040-B High-efficiency carbazole-based compound and organic electroluminescent device comprising same SK CHEMICALS CO LTD 2015-05-20 CN disclosed
US-20130119367-A1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME INDUSTRY ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) 2013-05-16 US disclosed
EP-2589643-A2 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME Industry-Academic Cooperation Foundation, Dankook University (KR) 2013-05-08 EP disclosed
CN-102959040-A High-efficiency carbazole-based compound and organic electroluminescent device comprising same UNIV DANKOOK IACF 2013-03-06 CN disclosed
EP-0176366-B1 IMPREGNATED CAPACITOR NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-01-25 EP disclosed
US-4631632-A METALLIZED POLYPROPYLENE FILM IMPREGNATED WITH DIELECTRIC HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-12-23 US disclosed
EP-0176366-A2 Impregnated capacitor NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130119367-A1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME PPIP5K2, INPP5B, EZH2 ALDH1A1 1956/4885HPGD 4030/4885ALOX15 867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.