Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptobenzothiazole SCHEMBL1042831 | 0.89 | POLB (0.60) | SMN1; SMN2ALOX15HTTHPGDTSHR | |
| 2-Mercaptobenzothiazole SCHEMBL27994442 | 0.88 | ADORA1 (0.54) | SMN1; SMN2ALOX15HTTHPGDTSHR | |
| 2-Mercaptobenzothiazole SCHEMBL28120542 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2ALOX15HTTHPGDTSHR | |
| 2-Mercaptobenzothiazole SCHEMBL28073413 | 0.86 | FBP1 (0.47) | SMN1; SMN2ALOX15HPGDHSD17B10POLB | |
| 2-Mercaptobenzothiazole SCHEMBL28019016 | 0.86 | ADORA1 (0.56) | SMN1; SMN2ALOX15TSHRPOLBALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL10595021 | 0.85 | KMT2A (0.49) | SMN1; SMN2ALOX15HTTHPGDTSHR | |
| 2-Mercaptobenzothiazole SCHEMBL28172014 | 0.84 | FBP1 (0.49) | SMN1; SMN2ALOX15HPGDHSD17B10POLB | |
| 2-Mercaptobenzothiazole SCHEMBL28866073 | 0.84 | ALDH1A1 (0.52) | SMN1; SMN2ALOX15HPGDTSHRHSD17B10 | |
| 2-Mercaptobenzothiazole SCHEMBL28760767 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2HPGDPOLBALDH1A1KMT2A | |
| 2-Mercaptobenzothiazole SCHEMBL8965658 | 0.83 | ADORA1 (0.49) | SMN1; SMN2ALOX15HTTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275523-B1 | CLEANING AGENT AND CLEANING METHOD FOR RIDDING TITANIUM AND TITANIUM ALLOY BUILDING MATERIALS OF DISCOLORATION | NIPPON STEEL & SUMITOMO METAL CORP (JP) | 2016-06-08 | — | — | EP | disclosed |
| EP-1548095-B1 | CLEANING AGENT AND CLEANING METHOD FOR RIDDING TITANIUM AND TITANIUM ALLOY BUILDING MATERIALS OF DISCOLORATION | NIPPON STEEL CORP (JP) | 2012-09-12 | — | — | EP | disclosed |
| EP-2275523-A2 | Cleaning agent and cleaning method for ridding titanium and titanium alloy building materials of discoloration | Nippon Steel Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-7547671-B2 | Discoloration removal cleaning agent for titanium and titanium alloy building materials, and discoloration removal cleaning method | NIPPON STEEL CORPORATION (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20050148481-A1 | Cleaning agent and cleaning method for ridding titanium and titanium alloy building materials of discoloration | NIPPON STEEL CORPORATION (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1548095-A1 | CLEANING AGENT AND CLEANING METHOD FOR RIDDING TITANIUM AND TITANIUM ALLOY BUILDING MATERIALS OF DISCOLORATION | NIPPON STEEL CORPORATION (JP) | 2005-06-29 | — | — | EP | disclosed |