Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666827 | 0.87 | ALDH1A1 (0.44) | AKR1B1HSD17B10GAAALDH1A1TSHR | |
| SCHEMBL8668157 | 0.87 | AKR1B1 (0.52) | AKR1B1HSD17B10GAAPDE4DALDH1A1 | |
| SCHEMBL3328675 | 0.80 | AKR1B1 (0.50) | AKR1B1HSD17B10GAAPDE4DALDH1A1 | |
| SCHEMBL8667611 | 0.78 | AKR1B1 (0.55) | AKR1B1HSD17B10GAAPDE4DALDH1A1 | |
| SCHEMBL30093426 | 0.77 | AKR1B1 (0.53) | AKR1B1HSD17B10GAAPDE4DALDH1A1 | |
| SCHEMBL10850347 | 0.75 | ALDH1A1 (0.44) | AKR1B1HSD17B10GAAALDH1A1TSHR | |
| SCHEMBL11471263 | 0.74 | PKM (0.43) | HSD17B10GAAPDE4DALDH1A1TSHR | |
| SCHEMBL24495402 | 0.74 | CLCN2 (0.43) | PDE4DALDH1A1CLCN2MEN1KMT2A | |
| 3,6 Dichloromethoxybenzoic Acid SCHEMBL9627578 | 0.74 | ALDH1A1 (0.69) | AKR1B1HSD17B10GAAALDH1A1TSHR | |
| SCHEMBL4401849 | 0.73 | GAA (0.44) | AKR1B1HSD17B10GAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960457-A | Substituted 1,3-diphenyl pyrrolidones and their use as herbicides | ICI AMERICAS INC. (US) | 1990-10-02 | — | — | US | disclosed |