Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420023 | 1.00 | TRHR (0.46) | TRHR | |
| SCHEMBL7620690 | 0.85 | TRHR (0.50) | TRHR | |
| Bromide SCHEMBL10345827 | 0.84 | TRHR (0.49) | TRHR | |
| SCHEMBL10420021 | 0.80 | OPRM1 (0.41) | TRHR | |
| SCHEMBL1000429 | 0.80 | DPP4 (0.44) | TRHR | |
| SCHEMBL2182026 | 0.80 | DPP4 (0.44) | TRHR | |
| SCHEMBL1000430 | 0.80 | DPP4 (0.44) | TRHR | |
| SCHEMBL2536244 | 0.79 | TRHR (0.49) | TRHR | |
| Bromide SCHEMBL7325997 | 0.79 | DPP4 (0.43) | TRHR | |
| Bromide SCHEMBL7325613 | 0.79 | DPP4 (0.43) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906614-A | Method of treating posttraumatic nervous injuries with dipeptide derivatives | GRUENENTHAL GMBH (DE) | 1990-03-06 | — | — | US | disclosed |