Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420192 | 0.81 | PDK1 (0.61) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL10420560 | 0.80 | PDK1 (0.46) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL10420550 | 0.78 | PDK1 (0.76) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL7520916 | 0.76 | KMT2A (0.55) | ALDH1A1GPR35RORCKMT2ARAB9A | |
| SCHEMBL9869447 | 0.74 | PDK1 (0.49) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL10421837 | 0.73 | VCAM1 (0.38) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL10420551 | 0.73 | KMT2A (0.61) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9825041 | 0.73 | ALDH1A1 (0.48) | ALDH1A1ADRA2AADRA2BADRA2CGPR35 | |
| SCHEMBL10421023 | 0.72 | AR (0.52) | ALDH1A1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL8554495 | 0.72 | ALDH1A1 (0.47) | ALDH1A1ADRA2AADRA2BADRA2CGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962284-A | HERBICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1990-10-09 | — | — | US | claimed |
| US-4826841-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | claimed |
| US-4992471-A | Fluorinated carboxanilide | LILLY INDUSTRIES LIMITED (GB) | 1991-02-12 | — | — | US | disclosed |
| US-4962284-A | HERBICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4826841-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0238351-A2 | Molluscicides | LILLY INDUSTRIES LIMITED (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0197756-A2 | Alkanoyl anilides | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0197451-A2 | Energy submetering system | HONEYWELL INC. (US) | 1986-10-15 | — | — | EP | disclosed |