Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575373 | 0.81 | MAPT (0.37) | ALDH1A1SMN1; SMN2MDM2MAPTKDM4E | |
| SCHEMBL16324473 | 0.78 | L3MBTL1 (0.35) | ALDH1A1SMN1; SMN2MDM2MAPTPOLB | |
| SCHEMBL3676705 | 0.74 | MAPT (0.38) | ALDH1A1SMN1; SMN2MAPTPOLBHTT | |
| SCHEMBL6036197 | 0.73 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2MAPTPOLBNPC1 | |
| SCHEMBL10420573 | 0.73 | MAPT (0.35) | ALDH1A1SMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL64089 | 0.73 | MAPT (0.35) | ALDH1A1SMN1; SMN2MDM2MAPTKDM4E | |
| SCHEMBL8953652 | 0.71 | MAPT (0.45) | ALDH1A1SMN1; SMN2MDM2MAPTKDM4E | |
| SCHEMBL5289525 | 0.71 | PTPRA (0.37) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4000254 | 0.70 | MAPT (0.40) | ALDH1A1SMN1; SMN2MAPTKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL8632041 | 0.70 | ALDH1A1 (0.32) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039087-A2 | INDOLINE DERIVATIVES AND USES THEREOF | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-04-03 | — | — | WO | disclosed |