Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422231 | 1.00 | HCAR3 (0.38) | HCAR3ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL9589970 | 0.84 | HPGD (0.40) | HPGDGAASMN1; SMN2RAB9A | |
| SCHEMBL10843040 | 0.84 | HPGD (0.40) | HPGDGAASMN1; SMN2RAB9A | |
| SCHEMBL9589976 | 0.84 | HPGD (0.40) | HPGDGAASMN1; SMN2RAB9A | |
| SCHEMBL5776553 | 0.81 | HPGD (0.54) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL10575701 | 0.81 | HPGD (0.54) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL9744912 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9689334 | 0.79 | CRBN (0.37) | HPGDGAASMN1; SMN2RAB9ATDP1 | |
| SCHEMBL9689331 | 0.79 | CRBN (0.37) | HPGDGAASMN1; SMN2RAB9ATDP1 | |
| SCHEMBL10883759 | 0.77 | HPGD (0.46) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965396-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1990-10-23 | — | — | US | disclosed |