Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863359 | 0.83 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CTSDKMT2ATDP1 | |
| SCHEMBL10422233 | 0.80 | HCAR3 (0.38) | ALDH1A1L3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL9092971 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CTSDKMT2AMEN1 | |
| SCHEMBL9092967 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CTSDKMT2AMEN1 | |
| SCHEMBL10718728 | 0.77 | CES1 (0.42) | ALDH1A1KMT2AMEN1TDP1MAPT | |
| SCHEMBL10631376 | 0.77 | CES1 (0.42) | ALDH1A1KMT2AMEN1TDP1MAPT | |
| SCHEMBL1694617 | 0.75 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CTSDKMT2AMEN1 | |
| SCHEMBL15180828 | 0.75 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CTSDKMT2AMEN1 | |
| SCHEMBL1670667 | 0.73 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1CTSDKMT2AMEN1 | |
| SCHEMBL31542074 | 0.73 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1CTSDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138088-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-11 | — | — | US | claimed |
| US-4965396-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1990-10-23 | — | — | US | claimed |
| US-5138088-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-11 | — | — | US | disclosed |
| US-5138088-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-11 | — | — | US | disclosed |
| US-5138088-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-11 | — | — | US | disclosed |
| US-4965396-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1990-10-23 | — | — | US | disclosed |
| US-4965396-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1990-10-23 | — | — | US | disclosed |
| US-4965396-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1990-10-23 | — | — | US | disclosed |