Glutamine

SCHEMBL10423656

CC(C)C[C@H](N)C(=O)OC(=O)CN.CC(C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)OC(=O)[C@@H](N)CCCCN.CC[C@H](C)[C@H](N)C(=O)O[C@H](C)[C@H](N)C(=O)OC(=O)[C@@H](N)COC(=O)[C@@H](N)CCCCN.CSCC[C@H](N)C(=O)O.C[C@@H](OC(=O)[C@@H]1CCCN1)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.C[C@H](N)C(=O)OC[C@H](N)C(=O)OC[C@H](N)C(=O)Oc1ccc(C[C@H](N)C(=O)OC(=O)[C@@H](N)CC(N)=O)cc1.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)Oc1ccc(C[C@H](N)C(=O)O)cc1.NCC(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](COC(=O)[C@@H]1CCCN1)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARD PTGS1 PTGS2 dacA dacB dacC ftsI mrcA mrcB mrdA

The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Glutamine SCHEMBL10424734	0.91	—	—
Histidine SCHEMBL9538044	0.83	CRHR1 (0.34)	—
Tyrosine SCHEMBL6253682	0.81	REN (0.31)	—
Tryptophan SCHEMBL5820703	0.80	PTH1R (0.39)	—
Phenylalanine SCHEMBL6479234	0.80	GLP1R (0.35)	—
Tryptophan SCHEMBL9295342	0.78	PTH1R (0.40)	—
Glutamine SCHEMBL6546514	0.78	KDM1A (0.34)	—
Tryptophan SCHEMBL8412516	0.78	GHSR (0.33)	—
Arginine SCHEMBL6482306	0.78	PTH1R (0.40)	—
Phenylalanine SCHEMBL28640115	0.78	REN (0.32)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4929718-A	Synthetic noxiustoxin related peptides	UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (MX)	1990-05-29	—	—	US	disclosed