Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599332 | 0.86 | L3MBTL1 (0.40) | AKT1ALDH1A1LMNAHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL11597784 | 0.85 | L3MBTL1 (0.40) | AKT1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4322599 | 0.82 | L3MBTL1 (0.46) | AKT1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4318450 | 0.82 | L3MBTL1 (0.46) | AKT1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL11418387 | 0.80 | FNTA (0.44) | AKT1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL5967875 | 0.78 | L3MBTL1 (0.45) | AKT1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL11598951 | 0.78 | CCKBR (0.46) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL7310468 | 0.77 | NPC1 (0.41) | ALDH1A1MEN1KMT2ASLC6A4 | |
| SCHEMBL7320870 | 0.77 | MEN1 (0.50) | AKT1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL10423904 | 0.77 | AKT1 (0.41) | AKT1ALDH1A1LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918105-A | Novel compounds with collagenase-inhibiting activity, a process for their preparation and pharmaceutical compositions in which these compounds are present | SA LABORATOIRE ROGER BELLON (FR) | 1990-04-17 | — | — | US | disclosed |