SCHEMBL10424314

SCHEMBL10424314

O=C1c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)N1c1cc(Br)c(S(=O)(=O)c2c(Br)cc(N3C(=O)c4c(Cl)c(Cl)c(Cl)c(Cl)c4C3=O)cc2Br)c(Br)c1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.50
CA2 P00918 8/20 0.50
CA7 P43166 8/20 0.50
CA9 Q16790 5/20 0.50
CA12 O43570 4/20 0.50
DPP8 Q6V1X1 1/20 0.41
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9438335 0.82 CA1 (0.40) CA1CA2CA7CA9CA12
SCHEMBL9438238 0.82 CA1 (0.49) CA1CA2CA7CA9CA12
SCHEMBL1899173 0.77 CA1 (0.53) CA1CA2CA7CA9CA12
SCHEMBL9438261 0.76 CA2 (0.40) CA1CA2CA7CA9CA12
SCHEMBL9438283 0.75 CA9 (0.48) CA1CA2CA7CA9CA12
SCHEMBL1811288 0.71 CA9 (0.71) CA1CA2CA7CA9CA12
SCHEMBL9438304 0.70 CA1 (0.40) CA1CA2CA7CA9CA12
SCHEMBL9438287 0.69 CA2 (0.74) CA1CA2CA7CA9CA12
SCHEMBL1906351 0.68 CA1 (0.45) CA1CA2CA7CA9CA12
SCHEMBL10976600 0.66 CA9 (0.65) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4940802-A 4,4'-bis(phthalimido)diphenyl sulfone compounds, processes for their production and flame retardant polymer compositions containing them TOSOH CORPORATION (JP) 1990-07-10 US disclosed