Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15389016 | 0.75 | TSHR (0.41) | TSHRHPGDALDH1A1HSD17B10MAPK1 | |
| SCHEMBL28098483 | 0.68 | ALDH1A1 (0.48) | TSHRHPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL15389443 | 0.67 | TSHR (0.46) | TSHRALDH1A1KDM4EMAP2K1CA1 | |
| SCHEMBL7760077 | 0.65 | TSHR (0.50) | TSHRHPGDALDH1A1MAPK1TDP1 | |
| SCHEMBL15548028 | 0.63 | MAOA (0.55) | TSHRHPGDALDH1A1TDP1KDM4E | |
| SCHEMBL15389751 | 0.63 | AR (0.43) | TSHRHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5251007 | 0.61 | TSHR (0.44) | TSHRHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL6231963 | 0.61 | TSHR (0.56) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| Water SCHEMBL19410621 | 0.61 | TSHR (0.63) | TSHRHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL29352197 | 0.61 | TSHR (0.63) | TSHRHPGDALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898895-A | Antifouling pain having a polyacrylate component with pendent silyl or siloxane groups | NIPPON OIL AND FATS CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |