Potassium Ion

SCHEMBL10424992

Cn1nnnc1C(/C=C/C(O)CC(O)CC(=O)[O-])=C(c1ccc(F)cc1)c1ccc(F)cc1.[K+]

nearest known ligand 0.96

Known targets — ChEMBL curated mechanism

AGTR1 DHFR GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GART NR3C2 PBP2X PTGS1 PTGS2 VKORC1 bla blaT-3 blaT-4 blaT-5 blaT-6 dacA dacB dacC folA ftsI mrcA mrcB mrdA pbp1a pbp1b pbp2a pbp2b pbp3 pol thyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	HMGCR	P04035	3/20	0.96

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Potassium Ion SCHEMBL10424994	1.00	HMGCR (0.96)	HMGCR
SCHEMBL9727155	0.98	HMGCR (1.00)	HMGCR
SCHEMBL9727153	0.98	HMGCR (1.00)	HMGCR
SCHEMBL30661850	0.98	HMGCR (1.00)	HMGCR
SCHEMBL9726527	0.93	HMGCR (0.90)	HMGCR
SCHEMBL9726534	0.93	HMGCR (0.90)	HMGCR
SCHEMBL637921	0.90	HMGCR (0.82)	HMGCR
SCHEMBL637920	0.90	HMGCR (0.82)	HMGCR
SCHEMBL9288114	0.90	HMGCR (0.82)	HMGCR
SCHEMBL6258027	0.90	HMGCR (0.82)	HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4897490-A	DERIVATIVES OF BETA-HYDROXY,OMEGA-DIPHENYL,TETRAZOL-5-YL ALK-OMEGA-ENOIC ACID, ESTER OR LACTONE	BRISTOL-MEYERS COMPANY (US)	1990-01-30	—	—	US	claimed
WO-1988006584-A1	ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS	BRISTOL-MYERS COMPANY (US)	1988-09-07	—	—	WO	claimed