SCHEMBL2879029

SCHEMBL2879029

COc1cc(OC)c2c(c1)C(=O)C[C@H](c1ccccc1)O2

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 5/20 0.67
KDM4E B2RXH2 2/20 0.67
ALDH1A1 P00352 2/20 0.67
HPGD P15428 2/20 0.67
HSD17B10 Q99714 2/20 0.67
CYP3A4 P08684 2/20 0.67
MAPK1 P28482 1/20 0.67
ABCB1 P08183 3/20 0.64
AR P10275 1/20 0.64
CYP19A1 P11511 4/20 0.61
MAOB P27338 3/20 0.61
MAPT P10636 2/20 0.59
MEN1 O00255 1/20 0.59
POLB P06746 1/20 0.59
GAA P10253 1/20 0.59
PABPC1 P11940 1/20 0.59
APEX1 P27695 1/20 0.59
RECQL P46063 1/20 0.59
KMT2A Q03164 1/20 0.59
EIF4H Q15056 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6723899 0.92 MAOB (0.62) ABCG2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL5085606 0.89 CYP19A1 (0.63) ABCG2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL5084282 0.86 ABCG2 (0.68) ABCG2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL3364494 0.86 MEN1 (0.65) ABCG2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL1242979 0.82 KDM4E (0.65) ABCG2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL10425232 0.82 ABCG2 (0.60) ABCG2KDM4EALDH1A1HPGDHSD17B10
Dimethylpinocembrin SCHEMBL2879027 0.81 ABCG2 (1.00) ABCG2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL17907269 0.80 MEN1 (0.67) ABCG2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL16894642 0.79 CYP19A1 (0.54) ABCG2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL126192 0.78 AR (1.00) ABCG2KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
US-20100098788-A1 Extracts of Curcuma and Methods of Use Thereof HERBALSCIENCE GROUP, LLC 2010-04-22 US claimed
WO-2010045577-A2 EXTRACTS OF CURCUMA AND METHODS OF USE THEREOF HERBALSCIENCE GROUP, LLC (US) 2010-04-22 WO claimed
EP-2484773-A2 Process for producing anthocyanins The Research Foundation of State University of New York (US) 2012-08-08 EP disclosed
EP-1784201-B1 PHYSIOLOGICALLY ACTIVE COMPOSITION AGAINST DIABETES PHYTOMEDICS INC (US) 2010-10-20 EP disclosed
US-7807422-B2 set of genes which encodes for enzymes which can convert substrates belonging to the general category of phenylpropanoids and result in the production of flavanones; without the need for chemical conversion THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2010-10-05 US disclosed
US-20100098788-A1 Extracts of Curcuma and Methods of Use Thereof HERBALSCIENCE GROUP, LLC 2010-04-22 US disclosed
WO-2010045577-A2 EXTRACTS OF CURCUMA AND METHODS OF USE THEREOF HERBALSCIENCE GROUP, LLC (US) 2010-04-22 WO disclosed
US-20090239272-A1 set of genes which encodes for enzymes which can convert substrates belonging to the general category of phenylpropanoids and result in the production of flavanones; without the need for chemical conversion KOFFAS MATTHEOS 2009-09-24 US disclosed
US-20090142425-A1 Physiologically active composition PHYTOMEDICS INCORPORATED 2009-06-04 US disclosed
US-7338791-B2 Introducing the set of genes into a heterologous host cell, allowing growth of the cells in a suitable medium such that the expression of the genes results in production of enzymes; culturing the cell under conditions permitting the synthesis of the flavonoid by the cells; isolating s flavonoids THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2008-03-04 US disclosed
WO-2006010560-A2 PHYSIOLOGICALLY ACTIVE COMPOSITION CARGILL, INCORPORATED (US) 2006-02-02 WO disclosed
US-20060019334-A1 Introducing the set of genes into a heterologous host cell, allowing growth of the cells in a suitable medium such that the expression of the genes results in production of enzymes; culturing the cell under conditions permitting the synthesis of the flavonoid by the cells; isolating s flavonoids NATIONAL SCIENCE FOUNDATION 2006-01-26 US disclosed
WO-2006010117-A2 PRODUCTION OF FLAVONOIDS BY RECOMBINANT MICROORGANISMS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2006-01-26 WO disclosed
EP-0139614-B1 PHARMACEUTICAL PREPARATIONS CONTAINING FLAVANONE OR THIOFLAVANONE DERIVATIVES, THE USE THEREOF, NOVEL FLAVANONES AND THIOFLAVANONES, AND PROCESSES FOR THEIR MANUFACTURE Zyma SA (CH) 1990-08-22 EP disclosed
US-4935441-A Flavene and thioflavene derivates, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter ZYMA SA (CH) 1990-06-19 US disclosed
US-4885298-A Pharmaceutical preparations containing flavanone or thioflavanone derivatives the use thereof, novel flavanones and thioflavanones, and processes for their manufacture ZYMA SA (CH) 1989-12-05 US disclosed
EP-0139615-B1 FLAVENE AND THIOFLAVENE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SUCH COMPOUNDS, AND THE USE OF THE LATTER Zyma SA (CH) 1989-04-19 EP disclosed
EP-0139615-A2 Flavene and thioflavene derivatives, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter Zyma SA (CH) 1985-05-02 EP disclosed
EP-0139614-A2 Pharmaceutical preparations containing flavanone or thioflavanone derivatives, the use thereof, novel flavanones and thioflavanones, and processes for their manufacture Zyma SA (CH) 1985-05-02 EP disclosed