Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19214803 | 0.73 | FDPS (0.47) | FDPSFBP1SLC6A3ALDH1A1TSHR | |
| SCHEMBL11002316 | 0.72 | FDPS (0.37) | FDPSFBP1SLC6A3ALDH1A1TSHR | |
| SCHEMBL17504097 | 0.72 | CTSK (0.34) | FDPSFBP1SLC6A3 | |
| SCHEMBL12854060 | 0.72 | — | — | |
| SCHEMBL8661610 | 0.71 | FDPS (0.39) | FDPSFBP1SLC6A3ALDH1A1TSHR | |
| Bromide SCHEMBL11003437 | 0.71 | FDPS (0.36) | FDPSFBP1SLC6A3ALDH1A1TSHR | |
| SCHEMBL11445384 | 0.71 | FDPS (0.42) | FDPSFBP1SLC6A3ALDH1A1TSHR | |
| SCHEMBL3407472 | 0.68 | — | — | |
| SCHEMBL155115 | 0.68 | — | — | |
| SCHEMBL17504072 | 0.68 | SLC6A3 (0.51) | FDPSSLC6A3ALDH1A1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904792-A | N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| US-4760075-A | Miticides | ELI LILLY AND COMPANY (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0091220-B1 | THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELI LILLY AND COMPANY (US) | 1987-05-13 | — | — | EP | disclosed |
| US-4474794-A | N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds | ELI LILLY AND COMPANY (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0091220-A2 | Thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1983-10-12 | — | — | EP | disclosed |
| US-4382090-A | N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |