Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480839 | 0.88 | SLC6A3 (0.42) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31570743 | 0.75 | SLC6A3 (0.57) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17504095 | 0.74 | SLC6A3 (0.60) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8722436 | 0.71 | GRIN2D (0.53) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30380236 | 0.71 | SLC6A3 (0.53) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8034456 | 0.71 | GRIN2D (0.53) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11445384 | 0.69 | FDPS (0.42) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28804693 | 0.69 | SLC6A3 (0.50) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10425543 | 0.68 | FDPS (0.37) | SLC6A3CYP2C19TSHRALDH1A1FDPS | |
| SCHEMBL17504062 | 0.68 | SLC6A3 (0.49) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2985279-B1 | Heterocyclic compounds with working memory enhancing activity | RED BULL GMBH (AT) | 2017-08-02 | — | — | EP | claimed |
| US-20170174642-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | COGMOTIV FLEXCO (AT) | 2017-06-22 | — | — | US | claimed |
| WO-2016023997-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | RED BULL GMBH (AT) | 2016-02-18 | — | — | WO | claimed |
| EP-2985279-A1 | Heterocyclic compounds with working memory enhancing activity | Red Bull GmbH (AT) | 2016-02-17 | — | — | EP | claimed |
| US-10221147-B2 | Heterocyclic compounds with working memory enhancing activity | RED BULL GMBH (AT) | 2019-03-05 | — | — | US | disclosed |
| US-10221147-B2 | Heterocyclic compounds with working memory enhancing activity | RED BULL GMBH (AT) | 2019-03-05 | — | — | US | disclosed |
| EP-2985279-B1 | Heterocyclic compounds with working memory enhancing activity | RED BULL GMBH (AT) | 2017-08-02 | — | — | EP | disclosed |
| US-20170174642-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | COGMOTIV FLEXCO (AT) | 2017-06-22 | — | — | US | disclosed |
| WO-2016023997-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | RED BULL GMBH (AT) | 2016-02-18 | — | — | WO | disclosed |
| EP-2985279-A1 | Heterocyclic compounds with working memory enhancing activity | Red Bull GmbH (AT) | 2016-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174642-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | TAAR1, ACHE, RIF1 | SLC6A3 683/4885CYP1A2 514/4885CYP3A4 1357/4885 |
| US-10221147-B2 | Heterocyclic compounds with working memory enhancing activity | TAAR1, ACHE, RIF1 | SLC6A3 683/4885CYP1A2 514/4885CYP3A4 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.