SCHEMBL10425908

SCHEMBL10425908

NC(=O)N(OCCc1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
TDP1 Q9NUW8 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPK1 P28482 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.43
GLA P06280 1/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
HIF1A Q16665 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
HCAR2 Q8TDS4 1/20 0.41
FFAR1 O14842 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2641140 0.83 ALDH1A1 (0.38) LMNATDP1NPC1RAB9AL3MBTL1
SCHEMBL7667460 0.83 ALDH1A1 (0.47) LMNATDP1NPC1RAB9AL3MBTL1
SCHEMBL11350559 0.81 LMNA (0.43) LMNATDP1NPC1RAB9AL3MBTL1
SCHEMBL11329965 0.80 KDM4E (0.40) LMNATDP1ALDH1A1SMN1; SMN2HPGD
SCHEMBL8395346 0.79 CYP3A4 (0.44) LMNATDP1NPC1RAB9AL3MBTL1
SCHEMBL2640938 0.79 ALDH1A1 (0.42) LMNAALDH1A1MAPK1SMN1; SMN2TSHR
SCHEMBL18554188 0.78 CYP3A4 (0.50) LMNATDP1NPC1RAB9AL3MBTL1
SCHEMBL5510643 0.77 ALDH1A1 (0.44) LMNANPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL28643941 0.77 NPSR1 (0.38) TDP1NPC1RAB9AL3MBTL1ALDH1A1
SCHEMBL27399370 0.76 LMNA (0.52) LMNANPC1RAB9AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4959092-A Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient MITSUBISHI KASEI CORPORATION (JP) 1990-09-25 US disclosed
EP-0293839-A2 Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient MITSUBISHI KASEI CORPORATION (JP) 1988-12-07 EP disclosed