Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11350559 | 0.87 | LMNA (0.43) | KDM4ELMNATDP1HCAR2ALDH1A1 | |
| SCHEMBL10425908 | 0.80 | LMNA (0.47) | LMNATDP1HCAR2ALDH1A1CHRM5 | |
| SCHEMBL7860796 | 0.75 | KMT2A (0.41) | KDM4ELMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3842681 | 0.74 | TAAR1 (0.48) | TDP1ALDH1A1NPY5RTAAR1 | |
| SCHEMBL11037902 | 0.72 | IDO1 (0.41) | — | |
| SCHEMBL11037899 | 0.72 | IDO1 (0.41) | — | |
| SCHEMBL20766982 | 0.71 | ALDH1A1 (0.39) | LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL597723 | 0.70 | TAAR1 (0.52) | TDP1ALDH1A1TAAR1 | |
| SCHEMBL4912310 | 0.70 | MGLL (0.55) | TDP1HCAR2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5509056 | 0.70 | KMT2A (0.54) | TDP1ALDH1A1HPGDSMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308213-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-29 | — | — | US | disclosed |