Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL10425568 | 0.96 | HTR1A (0.44) | HTR1ACYP1A2CYP2D6CYP2C9HSD17B10 | |
| SCHEMBL10425557 | 0.91 | GABRP (0.40) | HTR1ACYP1A2CYP2D6DRD2DRD4 | |
| SCHEMBL10425551 | 0.91 | GABRP (0.43) | HTR1ACYP1A2CYP2D6DRD2DRD3 | |
| Dimethylamine SCHEMBL10426045 | 0.88 | GABRP (0.38) | HTR1ACYP1A2CYP2D6DRD2DRD4 | |
| SCHEMBL10426693 | 0.87 | GABRP (0.38) | HTR1ADRD2DRD3GABRPGABRD | |
| SCHEMBL10425565 | 0.85 | GABRP (0.43) | HTR1ACYP1A2CYP2D6DRD2DRD3 | |
| SCHEMBL10425570 | 0.84 | G6PD (0.35) | HTR1ADRD2DRD3GABRPGABRD | |
| SCHEMBL10425883 | 0.83 | G6PD (0.41) | HTR1ADRD2DRD1DRD3GABRP | |
| SCHEMBL10426708 | 0.82 | G6PD (0.33) | HTR1ACYP1A2CYP2D6GABRPGABRD | |
| SCHEMBL10425559 | 0.82 | HTR2A (0.42) | DRD2DRD3GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908394-A | For polyurethane formation | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-03-13 | — | — | US | claimed |
| EP-0300349-A1 | Non-fugitive diaminobenzoate catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | claimed |
| US-4908394-A | For polyurethane formation | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-03-13 | — | — | US | disclosed |
| EP-0300349-A1 | Non-fugitive diaminobenzoate catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | disclosed |