Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRE | P78334 | 2/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425557 | 0.94 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10425551 | 0.94 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Dimethylamine SCHEMBL10426045 | 0.91 | GABRP (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10426616 | 0.90 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10426711 | 0.90 | SCN1A (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3447161 | 0.87 | BID (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10426044 | 0.87 | TBK1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29144911 | 0.86 | KAT8 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10426164 | 0.85 | HTR1A (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10426162 | 0.84 | SIGMAR1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908394-A | For polyurethane formation | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-03-13 | — | — | US | claimed |
| EP-0300349-A1 | Non-fugitive diaminobenzoate catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | claimed |
| US-4908394-A | For polyurethane formation | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-03-13 | — | — | US | disclosed |
| EP-0300349-A1 | Non-fugitive diaminobenzoate catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | disclosed |