Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 2/20 | 0.30 |
| ▸ | CCR5 | P51681 | 2/20 | 0.30 |
| ▸ | CCR8 | P51685 | 2/20 | 0.30 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19443439 | 0.85 | CCR1 (0.39) | CYP2A6CCR1CCR5CCR8 | |
| SCHEMBL21340202 | 0.84 | PDXK (0.32) | PDXKCYP2A6 | |
| SCHEMBL26462240 | 0.82 | — | — | |
| SCHEMBL4944670 | 0.82 | CCR1 (0.34) | PDXKCYP2A6HDAC8CCR1CCR5 | |
| SCHEMBL29673267 | 0.82 | CCR1 (0.34) | PDXKCYP2A6HDAC8CCR1CCR5 | |
| SCHEMBL11830120 | 0.79 | NOS2 (0.40) | PDXKCYP2A6 | |
| SCHEMBL15417589 | 0.79 | CCR1 (0.39) | PDXKCYP2A6HDAC8CCR1CCR5 | |
| SCHEMBL9467052 | 0.77 | CCR1 (0.30) | CCR1CCR5CCR8 | |
| SCHEMBL1522103 | 0.77 | PDXK (0.35) | PDXKCYP2A6HDAC8CCR1CCR5 | |
| SCHEMBL25777478 | 0.76 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021225912-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | PLIANT THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| US-4943482-A | ADDITION COPOLYMER WITH SILVER OR PALLADIUM COATING | RHONE-POULENC CHIMIE (FR) | 1990-07-24 | — | — | US | disclosed |
| EP-0311476-A1 | Metallized particles of crosslinked functional polymers, their preparation and their use in producing electroconductive materials | RHONE-POULENC CHIMIE (FR) | 1989-04-12 | — | — | EP | disclosed |
| EP-0103538-A2 | Copolymers of vinylpyridine, process for their preparation and their use as sulphonate reagents | CIBA-GEIGY AG (CH) | 1984-03-21 | — | — | EP | disclosed |