SCHEMBL29673267

SCHEMBL29673267

C=Cc1ccnc(C)c1C

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.34
CCR5 P51681 3/20 0.34
CCR8 P51685 3/20 0.34
CYP2A6 P11509 1/20 0.34
HDAC8 Q9BY41 1/20 0.32
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
NPC1 O15118 1/20 0.32
HSP90AA1 P07900 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PDXK O00764 1/20 0.32
GRM4 Q14833 1/20 0.30
UHRF1 Q96T88 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4944670 1.00 CCR1 (0.34) CCR1CCR5CCR8CYP2A6HDAC8
SCHEMBL26345976 0.82 PDXK (0.34) CCR1CCR5CCR8NOS3NOS2
SCHEMBL10426328 0.82 PDXK (0.35) CCR1CCR5CCR8CYP2A6HDAC8
SCHEMBL1567878 0.78 NOS3 (0.30) NOS3NOS2
SCHEMBL4796219 0.77 CCR1 (0.54) CCR1CCR5CCR8CYP2A6NOS3
SCHEMBL19443439 0.77 CCR1 (0.39) CCR1CCR5CCR8CYP2A6
SCHEMBL25141754 0.75 PDE3B (0.34) NOS3NOS2
SCHEMBL11830120 0.75 NOS2 (0.40) CYP2A6NOS3NOS2PDXK
SCHEMBL19685357 0.75
SCHEMBL27453477 0.74 CCR1 (0.32) CCR1CCR5CCR8CYP2A6NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114644738-B Active nano emulsion and preparation method thereof 清华大学 2023-07-14 CN disclosed
CN-114644738-A Active nano latex and preparation method thereof 清华大学 2022-06-21 CN disclosed