Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477427 | 0.91 | ESR1 (0.46) | ESR1ESR2LMNATSHRCYP1A2 | |
| SCHEMBL14941251 | 0.87 | ESR1 (0.49) | ESR1ESR2LMNATSHRCYP1A2 | |
| SCHEMBL27930463 | 0.83 | HDAC3 (0.40) | ESR1ESR2LMNAHIF1AHDAC3 | |
| SCHEMBL10353444 | 0.83 | ESR1 (0.55) | ESR1ESR2LMNATSHRCYP1A2 | |
| SCHEMBL28898282 | 0.82 | ATM (0.53) | CYP1A2CYP2D6CYP2C19TDP1ELANE | |
| SCHEMBL7919741 | 0.82 | ATM (0.53) | CYP1A2CYP2D6CYP2C19TDP1ELANE | |
| SCHEMBL28857417 | 0.82 | ALOX5 (0.53) | LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL20138640 | 0.80 | ESR1 (0.44) | ESR1ESR2LMNATSHRCYP1A2 | |
| SCHEMBL10426648 | 0.79 | LMNA (0.46) | ESR1ESR2LMNATSHRCYP1A2 | |
| SCHEMBL10599433 | 0.78 | DRD3 (0.46) | ESR1ESR2LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107199794-B | Thermal recording medium containing chelating agent | 株式会社理光 | 2019-08-06 | — | — | CN | disclosed |
| US-4912079-A | Thermosensitive coloring layer | RICOH COMPANY, LTD. (JP) | 1990-03-27 | — | — | US | disclosed |