SCHEMBL28857417

SCHEMBL28857417

CCCC(C(=O)Oc1ccc(OCc2ccccc2)cc1)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.53
LMNA P02545 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAOB P27338 1/20 0.50
PRKCA P17252 2/20 0.49
PRKCD Q05655 2/20 0.49
FFAR1 O14842 1/20 0.49
NR4A1 P22736 1/20 0.49
NR4A2 P43354 1/20 0.49
NR4A3 Q92570 1/20 0.49
HDAC3 O15379 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC2 Q92769 1/20 0.48
NCOR2 Q9Y618 1/20 0.48
PSEN1 P49768 1/20 0.47
PSEN2 P49810 1/20 0.47
APH1B Q8WW43 1/20 0.47
NCSTN Q92542 1/20 0.47
APH1A Q96BI3 1/20 0.47
PSENEN Q9NZ42 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28898282 0.83 ATM (0.53) L3MBTL1
SCHEMBL7919741 0.83 ATM (0.53) L3MBTL1
SCHEMBL10410136 0.82 LTA4H (0.52) ALOX5LMNAL3MBTL1HDAC3HDAC1
SCHEMBL10426565 0.82 ESR1 (0.46) LMNAHDAC3HDAC1HDAC2
SCHEMBL7167438 0.80 MAOB (0.58) ALOX5LMNAL3MBTL1MAOBFFAR1
SCHEMBL22497335 0.80 LMNA (0.57) ALOX5LMNAL3MBTL1PRKCAPRKCD
SCHEMBL28842185 0.80 LMNA (0.57) ALOX5LMNAL3MBTL1PRKCAPRKCD
SCHEMBL27973274 0.80 LMNA (0.57) ALOX5LMNAL3MBTL1PRKCAPRKCD
SCHEMBL7908556 0.79 MAOB (0.56) ALOX5LMNAL3MBTL1MAOBFFAR1
SCHEMBL27973452 0.78 LMNA (0.65) ALOX5LMNAL3MBTL1MAOBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107857783-A (4 hydroxyphenyl) the amyl group β D glucopyranosides of salidroside analog 4,4 2 and its synthetic method 枣庄学院 2018-03-30 CN disclosed