Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | UNG | P13051 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428345 | 0.75 | MCL1 (0.30) | — | |
| SCHEMBL1441399 | 0.68 | HDAC8 (0.47) | UNGALDH1A1TRIM24TRIM33HDAC8 | |
| SCHEMBL16194600 | 0.68 | MEN1 (0.38) | PADI4ALDH1A1 | |
| SCHEMBL10428510 | 0.66 | KMT2A (0.41) | ALDH1A1HDAC8 | |
| SCHEMBL9521034 | 0.60 | MEN1 (0.32) | ALDH1A1 | |
| SCHEMBL14969038 | 0.58 | MET (0.38) | — | |
| SCHEMBL31430067 | 0.58 | ATM (0.41) | ALDH1A1 | |
| SCHEMBL10428742 | 0.56 | L3MBTL1 (0.36) | — | |
| SCHEMBL16655286 | 0.55 | ADORA2B (0.33) | — | |
| SCHEMBL3387788 | 0.54 | HDAC8 (0.51) | ALDH1A1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0176387-B1 | PYRROLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS PESTICIDES | ROUSSEL-UCLAF (FR) | 1990-11-22 | — | — | EP | disclosed |
| EP-0176387-A1 | Pyrrole derivatives, process for their preparation and their application as pesticides | ROUSSEL-UCLAF (FR) | 1986-04-02 | — | — | EP | disclosed |