Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520398 | 0.74 | — | — | |
| SCHEMBL9521247 | 0.73 | ADORA2B (0.34) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14969038 | 0.63 | MET (0.38) | MEN1KMT2A | |
| SCHEMBL10428345 | 0.61 | MCL1 (0.30) | — | |
| SCHEMBL10428510 | 0.61 | KMT2A (0.41) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL9519935 | 0.61 | — | — | |
| SCHEMBL10428332 | 0.60 | TAS2R14 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9522954 | 0.58 | — | — | |
| SCHEMBL28791760 | 0.57 | L3MBTL1 (0.59) | POLB | |
| SCHEMBL18569860 | 0.55 | MEN1 (0.36) | MEN1KMT2APOLBHSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300898-B1 | PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-03-10 | — | — | EP | disclosed |
| US-5008281-A | Insecticides, miticides, nematocides | ROUSSEL UCLAF (FR) | 1991-04-16 | — | — | US | disclosed |
| US-4925862-A | PESTICIDES | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |
| EP-0300898-A1 | Pyrethrinoid derivatives containing an N-heterocycle, processes and intermediates for their preparation, their use as pesticides and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-01-25 | — | — | EP | disclosed |