Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428523 | 0.87 | ALDH1A1 (0.48) | TSHRUSP2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5477997 | 0.85 | ALDH1A1 (0.51) | TSHRUSP2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9781403 | 0.84 | TSPO (0.51) | TSHRUSP2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9781285 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL10824297 | 0.82 | ALDH1A1 (0.62) | TSHRUSP2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9781408 | 0.81 | ALDH1A1 (0.47) | TSHRUSP2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10598874 | 0.78 | MEN1 (0.44) | TSHRALDH1A1SMN1; SMN2NPSR1MEN1 | |
| Teclozan SCHEMBL635666 | 0.78 | ALDH1A1 (0.43) | TSHRUSP2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9781395 | 0.76 | ALDH1A1 (0.43) | TSHRUSP2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9781284 | 0.75 | PSEN1 (0.51) | TSHRUSP2ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897109-A | ACYLAMINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |