Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 7/20 | 0.48 |
| ▸ | MGAM | O43451 | 6/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.48 |
| ▸ | SI | P14410 | 6/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428733 | 0.86 | KCNMA1 (0.62) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL4054573 | 0.85 | KCNMA1 (0.61) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL11440840 | 0.85 | KCNMA1 (0.61) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL24019555 | 0.83 | KCNMA1 (0.59) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL10428731 | 0.81 | KCNMA1 (0.61) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL19911475 | 0.80 | KCNMA1 (0.56) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL10428732 | 0.79 | MGAM (0.60) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL23638342 | 0.79 | DGAT1 (0.58) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL11358890 | 0.78 | KCNMA1 (0.57) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL1161338 | 0.77 | KCNMA1 (0.53) | KCNMA1GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942248-A | CARBAMYLATION OF AMINO ACIDS BY REACTION WITH TERT-ALKYL ESTER A OF 1H-BENZOTRIAZOLE-1-CARBOXYLIC ACID TO FOR BLOCKED AMINO GROUP | PPG INDUSTRIES, INC. (US) | 1990-07-17 | — | — | US | disclosed |