SCHEMBL23638342

SCHEMBL23638342

Cc1ccc2c(c1)nnn2C(=N)n1nnc2cc(C)ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.58
KCNMA1 Q12791 2/20 0.55
GAA P10253 7/20 0.43
MGAM O43451 6/20 0.43
AMY1A P0DUB6 6/20 0.43
SI P14410 6/20 0.43
MGAM2 Q2M2H8 6/20 0.43
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
TSHR P16473 1/20 0.39
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
NAMPT P43490 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PKM P14618 1/20 0.37
POLB P06746 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10428733 0.82 KCNMA1 (0.62) KCNMA1GAAMGAMAMY1ASI
SCHEMBL11440840 0.81 KCNMA1 (0.61) KCNMA1GAAMGAMAMY1ASI
SCHEMBL4054573 0.81 KCNMA1 (0.61) KCNMA1GAAMGAMAMY1ASI
SCHEMBL3279838 0.79 PKM (0.56) KCNMA1ALDH1A1LMNATSHRRAB9A
SCHEMBL24019555 0.79 KCNMA1 (0.59) KCNMA1GAAMGAMAMY1ASI
SCHEMBL10428583 0.79 KCNMA1 (0.59) KCNMA1GAAMGAMAMY1ASI
SCHEMBL11270062 0.79 KCNMA1 (0.46) KCNMA1GAAMGAMAMY1ASI
SCHEMBL19911475 0.76 KCNMA1 (0.56) KCNMA1GAAMGAMAMY1ASI
SCHEMBL28836689 0.74 KCNMA1 (0.54) DGAT1KCNMA1GAAMGAMAMY1A
SCHEMBL29728235 0.74 KCNMA1 (0.54) DGAT1KCNMA1GAAMGAMAMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US disclosed
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US disclosed
US-20230257727-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-08-17 US disclosed
US-20230257727-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-08-17 US disclosed
US-20230021091-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-01-19 US disclosed
US-20210214701-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2021-07-15 US disclosed