Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.39 |
| ▸ | THRA | P10827 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885875 | 0.81 | SMN1; SMN2 (0.35) | THRBTHRAKMT2AMEN1CYP1A2 | |
| SCHEMBL10887119 | 0.81 | THRB (0.40) | THRBTHRAKMT2AMEN1CYP1A2 | |
| SCHEMBL8755037 | 0.80 | ALDH1A1 (0.41) | THRBTHRAKMT2AMEN1CYP1A2 | |
| SCHEMBL6364273 | 0.80 | LMNA (0.45) | THRBTHRAKMT2AMEN1KDM4E | |
| SCHEMBL10428605 | 0.80 | THRB (0.44) | THRBTHRAKMT2AMEN1CYP1A2 | |
| SCHEMBL10888016 | 0.80 | CYP3A4 (0.34) | THRBTHRAKMT2AMEN1CYP1A2 | |
| SCHEMBL10428603 | 0.80 | MAPT (0.32) | THRBTHRAKMT2AMEN1KDM4E | |
| SCHEMBL10871957 | 0.79 | THRB (0.43) | THRBKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL10630301 | 0.79 | THRB (0.42) | THRBTHRAKMT2AMEN1KDM4E | |
| SCHEMBL10883638 | 0.79 | CYP3A4 (0.34) | THRBTHRAKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358524-A2 | Optical material composed of resin having high refractive index | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |