SCHEMBL6364273

SCHEMBL6364273

C=CCOc1c(Br)cc(C(CC)c2cc(Br)c(OCC=C)c(Br)c2)cc1Br

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
HPGD P15428 2/20 0.40
THRB P10828 3/20 0.37
THRA P10827 2/20 0.37
KMT2A Q03164 7/20 0.37
MEN1 O00255 6/20 0.37
MAPT P10636 4/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
HTT P42858 2/20 0.37
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37
RAB9A P51151 1/20 0.37
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
GAA P10253 3/20 0.35
TSHR P16473 1/20 0.35
BLM P54132 1/20 0.34
RUNX1 Q01196 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11120585 0.84 LMNA (0.36) LMNASMN1; SMN2HPGDKMT2AMEN1
SCHEMBL10824409 0.83 LMNA (0.43) LMNASMN1; SMN2HPGDKMT2AMEN1
SCHEMBL5590860 0.83 THRB (0.39) LMNASMN1; SMN2HPGDTHRBTHRA
SCHEMBL10428604 0.80 THRB (0.39) LMNASMN1; SMN2THRBTHRAKMT2A
SCHEMBL6578128 0.77 LMNA (0.47) LMNASMN1; SMN2HPGDKMT2AMEN1
SCHEMBL42433 0.76 LMNA (0.45) LMNASMN1; SMN2HPGDKMT2AMEN1
SCHEMBL7600877 0.76 LMNA (0.45) LMNASMN1; SMN2HPGDTHRBKMT2A
SCHEMBL10596654 0.75 THRB (0.39) LMNASMN1; SMN2THRBTHRAKMT2A
SCHEMBL4378900 0.75 LMNA (0.46) LMNASMN1; SMN2HPGDTHRBTHRA
SCHEMBL4441223 0.75 THRB (0.43) SMN1; SMN2THRBTHRAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105637022-B The pre-expanded particles of compound resin containing carbon black and its manufacturing method and foam molding 积水化成品工业株式会社 2019-03-01 CN disclosed
CN-105175917-A Flame-resistant expandable styrene polymer composition and manufacturing method thereof TIANJIN SITANLI NEW MATERIAL CO LTD 2015-12-23 CN disclosed
CN-104592662-A High-thermal-resistance expandable polystyrene (EPS) composition particles and preparation method thereof BEIJING SITANLI TECHNOLOGY CO LTD 2015-05-06 CN disclosed
EP-0783543-B1 MOLDABLE THERMOPLASTIC POLYMER FOAM BEADS KNAUS DENNIS A (US) 2005-11-30 EP disclosed
EP-0783543-A4 MOLDABLE THERMOPLASTIC POLYMER FOAM BEADS KNAUS DENNIS A (US) 1998-11-11 EP disclosed
US-5763498-A COMPRISING CROSSLINKED OR NONCROSSLINKED POLYMERS ANDBLOWING AGENT KNAUS DENNIS A (US) 1998-06-09 US disclosed
EP-0783543-A1 MOLDABLE THERMOPLASTIC POLYMER FOAM BEADS Knaus, Dennis A. (US) 1997-07-16 EP disclosed
US-5605937-A EXTRUSION UNDER PRESSURE; CROSSLINKING; CONTROLLINGTEMPERATURE TO ACHIEVE DESIRED CROSSLINKING KNAUS DENNIS A (US) 1997-02-25 US disclosed
WO-1996010600-A1 MOLDABLE THERMOPLASTIC POLYMER FOAM BEADS KNAUS DENNIS A (US) 1996-04-11 WO disclosed
EP-0273710-A2 Resin having high refractive index, process for producing said resin and optical materials composed of said resin Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1988-07-06 EP disclosed
EP-0115341-B1 GRANULAR ORGANOHALIDE FLAME RETARDANT ADDITIVE AND METHODS OF PREPARING THE SAME SEKISUI KASEIHIN KOGYO KABUSHIKI KAISHA (JP) 1987-09-30 EP disclosed
US-4530880-A Thermoplastic resin binder SEKISUI KASEIHIN KOGYO KABUSHIKI KAISHA (JP) 1985-07-23 US disclosed