Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177364 | 0.81 | KMT2A (0.51) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL5692460 | 0.79 | ALDH1A1 (0.50) | MAPK1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL10429070 | 0.78 | TPMT (0.50) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL10428832 | 0.77 | MEN1 (0.50) | MAPK1ALDH1A1ALOX12KMT2AMEN1 | |
| SCHEMBL10428879 | 0.75 | MEN1 (0.49) | MAPK1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL10428846 | 0.75 | ABCG2 (0.46) | ALDH1A1KMT2AMEN1KDM4ETUBB4A | |
| SCHEMBL10622361 | 0.74 | MEN1 (0.49) | MAPK1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL10428912 | 0.74 | ALDH1A1 (0.44) | MAPK1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9832697 | 0.74 | PDE4A (0.56) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL4797626 | 0.74 | TUBB4A (0.50) | ALDH1A1KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929741-A | ANTISECRETORY AGENTS, GASTRIC JUICE, ANTIULCER AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1990-05-29 | — | — | US | disclosed |