Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Hydroxybenzaldehyde SCHEMBL6942477 | 0.76 | ALDH5A1 (0.50) | ALDH1A1ALDH5A1ABATRAB9AKMT2A | |
| 4-Hydroxybenzaldehyde SCHEMBL7168177 | 0.68 | ALDH5A1 (0.76) | ALDH1A1ALDH5A1ABATRAB9AKMT2A | |
| 4-Hydroxybenzaldehyde SCHEMBL27689568 | 0.67 | ALDH5A1 (0.67) | ALDH1A1ALDH5A1ABATRAB9AKMT2A | |
| 4-Hydroxybenzaldehyde SCHEMBL27592772 | 0.66 | ALDH5A1 (0.89) | ALDH1A1ALDH5A1ABATRAB9AKMT2A | |
| 4-Hydroxybenzaldehyde SCHEMBL28460767 | 0.66 | ALDH5A1 (0.89) | ALDH1A1ALDH5A1ABATRAB9AKMT2A | |
| 4-Hydroxybenzaldehyde SCHEMBL19328157 | 0.66 | ALDH5A1 (1.00) | ALDH1A1ALDH5A1ABATRAB9AKMT2A | |
| 4-Hydroxybenzaldehyde SCHEMBL37193 | 0.66 | — | — | |
| SCHEMBL195687 | 0.64 | ALDH1A1 (1.00) | ALDH1A1ALDH5A1ABATRAB9AKMT2A | |
| 4-Hydroxybenzaldehyde SCHEMBL27479037 | 0.64 | ALDH5A1 (0.84) | ALDH1A1ALDH5A1ABATRAB9AKMT2A | |
| 4-Hydroxybenzaldehyde SCHEMBL2187647 | 0.64 | ALDH5A1 (0.94) | ALDH1A1ALDH5A1ABATRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402151-A1 | New 2, 5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |